
Join us in person for the
13th UK & Ireland Early Career Blood-Brain Barrier Symposium


PURPOSE
Organised by Doctor Adjanie Patabendige at Edge Hill Universty, the 2023 meeting of the UK & Ireland Early Career Blood-Brain Barrier (BBB) Society will take place on the 17th November 2023 in Edge Hill University, Ormskirk L39 4QP/
This meeting will provide a unique platform for early career BBB researchers to present their newest findings in both presentationand poster format. We welcome abstracts on all aspects of blood CNS barrier biology including blood brain barrier (BBB), blood–cerebrospinal barrier (B-CSF) and blood retina barrier (BRB). We have two amazing keynote speakers lined up and there are several prizes and awards for outstanding presentations from ECRs generously sponsored by Pharmidex, AFRUK and Edge Hill University.
17th November 2023 in Person
Agenda
Draft programme
From 10.00am: Registration and tea/coffee (Creative Edge, Edge Hill University)
10.30am: Welcome (Dr Adjanie Patabendige)
10.45am: Academic keynote presentation.
Prof Egle Solito (Queens Mary) The lifetime risk of metabolic disorders on the structural, functional, and immunological integrity of the blood-brain barrier: therapeutic avenues
11.30am: ECR presentations- Neuroinflammation at the Blood-Brain Barrier
Dr Conor McQuaid (University of Edinburgh) AAV-induced selective VAM expression triggers blood-brain barrier defects causing cognitive dysfunctions
Ms Megan Ritson (Royal Veterinary College, London) Repeated low-level inflammation leads to upregulation of the TNFα-CXCL10 signalling pathway in the cerebrovasculature in vitro.
Dr Cordelia Dunai (University of Liverpool) Biomarkers of neurological complications of COVID-19
12.15pm: ECR Lightening talks
Ceinwyn Cooper (Edge Hill University) Nanogels as a potential dementia treatment candidate:
development, functionality and preliminary BBB transport
Natalia Grzesik (Queen Mary University of London) Amyloid beta immunotherapy in Alzheimer’s disease: an in vitro study depicting the molecular mechanisms
Sarah Aimee Boardman (University of Liverpool) Investigating direct and indirect effects of viral infections on the brain and prevention via immune suppression
Camarra Jayde Nazha (Edge Hill University) Modelling blood-brain barrier disruption in atrial fibrillation
Melis Psirien (University College London) Transport across the BBB in health vs disease.
Eleanor Taylor-Chilton (University of Central Lancashire) Application of in vitro models: incorporating Blood brain barrier models with glioma, and the use of microfluidics.
Jack Corbett (Nottingham Trent University) Hypoxia induced HIF1α activity leads to alterations of
neuronal architecture in the dorsal horn.
Josephine Peddler (University of Liverpool) Novel, biologically relevant, in vitro model of the blood-brain tumour barrier
Ryan Duffy (University of Nottingham) Losartan induced astrocytic recovery in high fat diet may
alleviate neuropathic pain
1.00pm: Lunch and posters
2.15pm: Industry keynote presentation. Dr Reinhard Gabathuler (King’s College London) Development of new carrier technologies to cross the blood-brain barrier
3.00pm: ECR presentations- CNS Barriers in Health and Disease
Dr Yolanda Ohene (University of Manchester) Lung infection alters aquaporin-4 proteins at the blood-brain barrier in rat model of Alzheimer’s Disease detected by MRI
Dr Lydia Hardowar (Nottingham Trent University) Using novel techniques to investigate spinal pericyte and astrocyte interaction in high fat diet induced hyperglycaemia
Dr Arathyram Sasikala (University of Bradford) Self- powered nanoparticles for non-invasive blood-brain barrier modulation and glioblastoma treatment
Dr Joe Forth (University of Liverpool) Using the Granular Jamming Transition to 3D-Print a Blood-
Brain Barrier-on-a-Chip
4.15pm: Award presentation including David Begley Excellence Award for Young BBB Researchers (sponsored by Pharmidex)
4.45pm: Closing remarks (Dr Adjanie Patabendige and Dr David Dickens)
5.15pm: Drinks reception
Location: Creative Edge, Edge Hill University (https://www.edgehill.ac.uk/locations/)
Delegates will be provided with an unreserved parking permit (parking cannot be guaranteed) or a free one-day bus pass from Ormskirk bus/train station to Edge Hill University.
CONFERENCE REGISTRATION &
ABSTRACT SUBMISSION
Registration deadline: Closed
Abstracts in the area of blood-brain barrier (BBB), blood-cerebrospinal barrier (BCSFB) and blood-retina barrier (BRB) are welcome. Please submit your abstract directly to Brain_Barriers@edgehill.ac.uk
Abstracts must be submitted as a word document. Please follow the guidelines below.
Abstract title: limited to 25 words.
Abstract text: limited to 250 words, excluding references.
Abstract structure:
– Background and aims
– Methods
– Results
– Conclusions
When submitting your abstract, please use ABSTRACT_13th BBB symposium YOUR NAME in the subject line.
Please state your preferred presentation format (talk or poster).
Registration is free and lunch will be provided. In this regard, places will be limited so please register early and submit your abstracts as soon as possible

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