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1st UK and Ireland Blood-Brain Barrier Symposium
Dr Nacho Romero, Open University, was the host for the 1st UK & Ireland Early Career BBB Symposium. The BBB Symposium was held on the 25th of November 2011 at the Open University, Milton Keynes, UK. The keynote presentation for this symposium was given by Professor Joan Abbott, King’s College London. The symposium program is listed below:
10.30 -11.00 Coffee and registration
11.00-11.10 Welcome
Nacho Romero, The Open University
11.10-11.50 Keynote Lecture
The Blood-Brain Barrier, past, present and future. Joan Abbott, King’s College London
11.50-13.30 Session 1: Cellular interactions at the blood brain barrier
Chair: Larisa Mihoreanu, King’s College London
Investigating interactions between human neural stem cells and brain endothelial cells in co-culture systems. Chung-Hsing (Tony) Chou, KCL Institute of Psychiatry
Development of a three-dimensional model to study astrocyte-endothelial cell interactions. Sreekanth Reddy, The Open University
12.30-13.30 Lunch
1.30-14.50 Session 2: Inflammation at the blood brain barrier
Chair: Dongsheng Wu, The Open University
Sex dimorphism in inflammation: a role for Annexin A1 in mediating oestrogen effects on the blood-brain barrier. Enrico Cristante, William Harbey Research Institute, QMUL
Cytokine-induced miR-155 regulates brain endothelial permeability. Alejandro Lopez, Open University
An endothelial JNK-paxillin pathway regulates VE-cadherin internalisation and ICAM-1-mediated lymphocy te migration. Natalie Hudson, UCL Institute of Ophthalmology
Role of microRNAs in leukocyte adhesion to human brain endothelial cells. Camilla Cerutti, The Open University
14.50-15.20 Tea
Session 3: Transporters at the blood brain barrier and drug delivery
Chair: David Dickens, University of Liverpool
The role of the two drug efflux pumps in refractory epilepsy. Steffen Radisch, University of Liverpool
L-arginine, ADMA and the blood-brain barrier – Paradox no more. Mehmet Fidanboylu, King’s College London
An investigation of antiepileptic drug transport by the solute carrier transporter family. Hayley Jones, University of Liverpool
Functionalised carbon nanotubes for brain delivery in-vivo. Tzu-Wen Wang, King’s College London
16.40-17.00 General discussion and concluding remarks
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