Dr Nacho Romero, Open University, was the host for the 1st UK & Ireland Early Career BBB Symposium. The BBB Symposium was held on the 25th of November 2011 at the Open University, Milton Keynes, UK. The keynote presentation for this symposium was given by Professor Joan Abbott, King’s College London. The conference programme is available for download. The symposium program is listed below;


1st UK and Ireland Blood-Brain Barrier Symposium 2011

10.30 -11.00 Coffee and registration


11.00-11.10 Welcome

Nacho Romero, The Open University


11.10-11.50 Keynote Lecture

The Blood-Brain Barrier, past, present and future. Joan Abbott, King’s College London


11.50-13.30 Session 1: Cellular interactions at the blood brain barrier

Chair: Larisa Mihoreanu, King’s College London

Investigating interactions between human neural stem cells and brain endothelial cells in co-culture systems. Chung-Hsing (Tony) Chou, KCL Institute of Psychiatry

Development of a three-dimensional model to study astrocyte-endothelial cell interactions. Sreekanth Reddy, The Open University


12.30-13.30 Lunch


1.30-14.50 Session 2: Inflammation at the blood brain barrier

Chair:Dongsheng Wu, The Open University

Sex dimorphism in inflammation: a role for Annexin A1 in mediating oestrogen effects on the blood-brain barrier. Enrico Cristante, William Harbey Research Institute, QMUL

Cytokine-induced miR-155 regulates brain endothelial permeability. Alejandro Lopez, Open University

An endothelial JNK-paxillin pathway regulates VE-cadherin internalisation and ICAM-1-mediated lymphocy te migration. Natalie Hudson, UCL Institute of Ophthalmology

Role of microRNAs in leukocyte adhesion to human brain endothelial cells. Camilla Cerutti, The Open University


14.50-15.20 Tea


Session 3: Transporters at the blood brain barrier and drug delivery

Chair: David Dickens, University of Liverpool

The role of the two drug efflux pumps in refractory epilepsy. Steffen Radisch, University of Liverpool

L-arginine, ADMA and the blood-brain barrier – Paradox no more. Mehmet Fidanboylu, King’s College London

An investigation of antiepileptic drug transport by the solute carrier transporter family. Hayley Jones, University of Liverpool

Functionalised carbon nanotubes for brain delivery in-vivo. Tzu-Wen Wang, King’s College London


16.40-17.00 General discussion and concluding remarks


© 2015 by UK & Ireland Early Career Blood-Brain Barrier Symposium website created by David Dickens