9th UK & Ireland Early Career BBB Symposium
The 9th Annual UK & Ireland Early Career Blood Brain Barrier Symposium was held at the Open University, Milton Keynes on Friday the 22nd of November 2019.
09:30 -10:00 Registration at Berrill Lecture Theatre
10:05 Prof. Ignacio Romero (The Open University)
Welcome and Symposium presentation
First session chairs : Madeeha Hamid Sheikh (QUML) & Nayab Fatima (OU)
10:05 -10:55 Keynote speaker: Dr. Jane Preston (King’s College
"CNS mitochondrial disease caused by CoQ10 deficiency: CoQ10 homeostasis by the BBB explains why CoQ supplements have only transient therapeutic effect"
10:55 -11:15 Ester Pascual Baixauli (The Open University)
"Effect of high fat diet on choroid plexus in the female rat"
11:15 -11:35 Atieme J Ogbolosingha )Keele University)
"Potential role for astrocyte aquaporin 4 in the blood brain barrier in cerebral malaria"
11:35 -11:55 Dr. Zahraa S. Al Ahmady (University of Manchester)
"Blood-Brain Barrier Disruption Post Ischemic Stroke Enables Time dependent Targeting of the Lesioned Brain Using Lipid Nanoparticles"
11:55 -12:15 Joe Chouhan (University of Southampton)
"The neuroinflammatory response to Salmonella is disease progression dependent in the ME7 prion model of neurodegeneration"
12:15 -12:25 Wedad Alhassan K Mawkili (University of Liverpool)
"Identification of the Clozapine Transporter"
12:30 -14:00 Lunch and poster session
Second session chairs: Sonia Azeggagh (OU) & George Bryant (OU)
14:00 -14:50 Keynote speaker: Dr. Maxime Culot (Université d’Artois )
"Sharing my experience with grant writing and getting funds"
14:50 -15:10 Dr. Radka Gromnicova and Eduardo Frías Anaya (OU)
"How you can create 3D reconstruction of BBB at the electron microscopy level: Assessing age changes in BBB ultrastructure"
15:10 -15:30 Dr. Camilla Cerutti (University of Bristol)
"CDC42 targets regulate cancer cell interaction with endothelial cells in tumour progression"
15:30 15:40 Charlotte M. Stuart (University of Southampton)
"Haptoglobin and Blood Brain Barrier Permeability"
15:40 -16:00 Coffee break
Third session chairs: Dr. Nandita Rahatekar (OU) & David Roig Carles (OU)
16:00 -16:20 Basma Elbakary (Aston University)
"A dynamic perfusion based blood brain barrier model for cytotoxicity testing and drug permeation"
16:20 -16:40 Dr. Waseema Patel (University of Liverpool
"The Antidepressant AV-101 is a Substrate for LAT1 (SLC7A5) at the Blood-Brain Barrier"
16:40 -16:50 Mary Goodwin Trotman (University of Cambridge)
"Developing an hiPSC derived 3D in vitro model of the blood brain barrier to study COL4A1/2 cerebral small vessel disease"
16:50 -17:00 Sophie Quick (University of Edinburgh)
"Endothelial cell dysfunction as a mechanism for Cerebral Small Vessel Disease"
17:00 -17:10 Benjamin Roberts (University of Warwick)
"A Functional Circadian Clock within the Blood-Brain Barrier Controls Key Pharmacokinetic Properties"
17:10 -17:30 Dr. Swati Kumar (University of Warwick)
"Circadian permeability of an In Vitro Tri-Culture Model of Blood Brain Barrier"
17:30 -17:40 Eduardo Frías Anaya (The Open) Dr. David Dickens (University of Liverpool)
17:40 -19:00 Wine reception